Associate Director, Pharmacology    

This position is responsible for the design and execution of in vivo studies conducted in support of Alder Biopharmaceutical’s drug discovery and development programs. This individual will take the lead in interfacing with vendors to perform acute and chronic toxicology programs, assess lead candidate pharmacokinetic properties and characterization of therapeutic candidate efficacy in the appropriate in vivo setting. In this latter role, the individual will have hands-on responsibilities for heading the internal in vivo characterization efforts. This individual will have in-depth experience running both mechanistic and therapeutic models of cancer and/or inflammatory disease. Lastly, this individual will have the responsibility of drafting technical summary reports concerning the in vivo testing of molecules progressing to IND filings.

Qualifications:
This position requires a Ph.D., M.D. or D.V.M. and a minimum of 8 years of experience in the pharmaceutical or biotechnology sector. Significant experience in inflammation and cancer in vivo models is required. First hand experience with managing external studies is key. The preferred candidate will need to have contributed to therapeutic antibody IND filings. Strong capabilities in in vivo model design, FACS and ELISA methods are a must. This position requires excellent verbal and written communication skills as well as strong interpersonal skills.

Please send your cover letter and resume to hr@alderbio.com. When applying for this position, please reference job code #R09-02 and let us know how you heard about the opportunity.
Research Associate, In Vitro Cell Biology    

Alder Biopharmaceuticals is seeking an experienced and motivated Research Associate to join our discovery group in working towards the identification of novel therapeutic antibodies.

This individual will have responsibility for maintaining mammalian cell lines, cell transfection, and the development of ELISAs. In addition, he/she will be expected to develop, troubleshoot and execute functional assays, analyze data, and prepare technical reports.


Qualifications:
B.S. in the biological sciences with a minimum of 3 years experience in an industry setting. Prior research experience in the area of biopharmaceutical drug discovery is required and knowledge of biologics is highly preferred. Strong cellular biology skills including experience in tissue culture, the development of ELISAs and functional assays for the screening of therapeutic agents is essential. Experience with the development of cell based functional assays (proliferation/cytotoxicity assays) flow cytometry, reporter gene assays, and molecular biology techniques are preferred. He/she is expected to effectively manage laboratory data, be proficient in MS Office applications and have strong written and oral communications skills. Familiarity with preclinical models in immunology or oncology is a plus.

Please send your cover letter and resume to hr@alderbio.com. When applying for this position, please reference job code R10-05 and let us know how you heard about the opportunity.
Research Associate, ABS Cell Biology    

Alder Biopharmaceuticals is seeking an experienced and motivated Research Associate to join our Antibody Selection technology group in working towards the identification of novel therapeutic antibodies.

This individual will have responsibility for maintaining mammalian cell lines, assay development and validation including biochemical (ELISA) and cell based functional assays. In addition, the successful candidate will be involved in the development and adaptation of functional assays for high throughput screening, as well as all subsequent data analysis and technical report preparation.


Qualifications:
M.S. or B.S. in the biological sciences with a minimum of 3+ years experience in an industry setting. Prior research experience in the area of biopharmaceutical drug discovery is required and knowledge of biologics is highly preferred. Strong cellular biology skills including experience in tissue culture, the development of ELISAs and functional assays for the screening of therapeutic agents is essential. Experience with the development of cell based functional assays (proliferation/cytotoxicity assays) flow cytometry, reporter gene assays, and molecular biology techniques are preferred. He/she is expected to effectively manage laboratory data, be proficient in MS Office applications and have strong written and oral communications skills.

Please send your cover letter and resume to hr@alderbio.com. When applying for this position, please reference job code R10-07 and let us know how you heard about the opportunity.